| Catalog Code: | NB110-39056 |
| Product Type: | Primary Antibody |
| Product Name: | BACE1 Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 23621 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-BACE1 |
| Cross Reactivity: | Human. Other species not tested. |
| Species Summary: | Hu |
| Background: | Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved s |
| Alternate Names: | anti-ASP2 antibody, anti-BACE antibody, anti-HSPC104 antibody, anti-KIAA1149 antibody |
| Immunogen: | Synthetic peptide (exact sequence is proprietary information). |
| Epitope: | internal domain of human |
| Specificity: | This antibody is specific to the human BASE1 protein. |
| Purity: | peptide affinity purified |
| Buffer: | Phosphate buffered saline, |
| Packaging: | 0.05 mg peptide affinity purified Rabbit antisera. |
| Package Size: | 0.05 mg |
| Concentration: | 1 mg/ml |
| Uses: | This antibody is useful for immunohistochemistry. Optimal dilution to be determined by the researcher. |
| Application Summary: | IHC |
| General References: | 1. Sun X, He G, Qing H, Zhou W, Dobie F, Cai F, Staufenbiel M, Huang LE, and Song W. Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression. Proc Natl Acad Sci U S A (2006 Nov). 2. Durham TB, and Shepherd TA. |