| request information: |
|
| Catalog Code: | NB110-38898 |
| Product Name: | XRCC1 Antibody |
| Product Description: | Rabbit Polyclonal anti-XRCC1 |
| Clonality: | Polyclonal |
| ListPrice: | 365 |
| Gene ID: | 7515 |
| Immunogen: | The epitope recognized by this antibody maps to a region surrounding residues Ser 485 and Thr 488 of human X-ray Repair Complementing protein 1 using the numbering given in SwissProt entry P18887 (GeneID 7515). |
| Specificity: | This antibody is specific to the Phospho XRCC1 (S485/T488) protein. |
| Cross Reactivity: | Human and Mouse. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is used for imunohistochemistry. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. |
| Background: | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| Application Summary: | immunohistochemistry 1:100-1:500, |
| Species Summary: | Hu, Mu |
| Alternate Names: | anti-XRCC1 antibody, anti-X-ray Repair Complementing protein 1 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.09% Sodium Azide |
order or
more information: | company product webpage |