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| Catalog Code: | NB110-1790 |
| Product Name: | Desmin Antibody |
| Product Description: | Mouse Monoclonal anti-Desmin (DE-U-10) |
| Clone: | DE-U-10 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 8.0 mg/ml |
| Immunogen: | Full length native protein (purified) (Pig). |
| Specificity: | This antibody is specific for desmin as determined by indirect immunofluorescent staining methods. It specifically stains the wide desmin band of 50,000 to 55,000 molecular weight by immunoblotting methods. |
| Cross Reactivity: | Cross-reacts with Cat, Chicken, Cow, Goat, Hamster, Human, Mouse, Rabbit, Rat, Sheep, Snake and Lizard. Not yet tested in other species. |
| Packaging: | 0.1 ml Ascites Mouse ascites. |
| Uses: | Monoclonal anti-desmin may be used for immunocytochemical localization of intermediate filaments of the desmin group in all types of muscle cells and to localize desmin at the periphery of z-discs. |
| Localization: | Cytoplasmic |
| Background: | Desmin is the protein subunit of muscle-type intermediate filaments (IFs). Desmin is one of the five major groups of IFs and is found predominantly in skeletal, cardiac, and smooth muscle.DE-U-10 labels desmin in tumors derived from muscle tissue (leiomyomas and rhabdomyosarcomas) (Debus E et al.). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Ascites |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Ascitic fluid |
| Application Summary: | immunofluorescence 1/20, Western Blot , Immunocytochemistry , Immunohistochemistry-Paraffin |
| Species Summary: | Bv, Ch, Ha, Hu, Mu, Rt, Rb, Fe, Gt, Sh, |
| Alternate Names: | Anti-CMD1I antibody; Anti-CSM1 antibody Anti-CSM2 antibody; Anti-DES antibody; Anti-FLJ12025 antibody; Anti-FLJ39719 antibody; Anti-FLJ41013 antibody; Anti-FLJ41793 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 15mM sodium azide |
| General References: | This product has been used in:Debus E et al. Monoclonal antibodies to desmin, the muscle-specific intermediate filament protein. EMBO J 2:2305-12 (1983). |
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more information: | company product webpage |