| CatalogCode: | NB110-17898 |
| ProductName: | HLA ABC Antibody |
| Product Description: | Mouse Monoclonal anti-HLA ABC (W6/32) |
| Clone: | W6/32 |
| Clonality: | Monoclonal |
| Immunogen: | Tissue / cell preparation of membrane of tonsil cells (Human). |
| Specificity: | Recognises an antigenic determinant shared among products of the HLA A, B and C loci. The antibody recognises virtually all nucleated human cells. |
| CrossReactivity: | Cross-reacts with Cow, Cat, Human and Rhesus Macaque. Not yet tested in other species. |
| Packaging: | 0.1 mg Affinity purified Mouse ascites. |
| Uses: | FACS: Use 10 ul of the suggested working dilution to label 10<sup>6</sup> cells or 100 ul whole blood. |
| Localization: | Type I membrane protein. |
| Control: | Human tonsil tissue slides. |
| Background: | HLA-ABC antigen is present on most nucleated cells of humans and Old World monkeys. HLA CLass I is involved in the presentation of foreign antigens to the immune system. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG2a |
| Host_Name: | Mouse |
| Buffer: | Constituents: PBS. pH 7.4 |
| ListPrice: | 295 |
| AppSummary: | FACS, IHC-Fr, IHC-P, IP |
| SpeciesSummary: | Bv, Hu, Mk, Fe |
| ALTnames: | anti-Antigen Presenting Molecule antibody, anti-HLA Class I Histocompatibility Antigen A Alpha Chain antibody, anti-HLA Class I Histocompatibility Antigen B Alpha Chain antibody, anti-HLA Class I Histocompatibility Antigen C Alpha Chain antibody, anti-Human Leucocyte Antigen C antibody, anti-Major Histocompatibility Complex Class I A antibody, anti-Major Histocompatibility Complex Class I B antibody, anti-Major Histocompatibility Complex Class I C antibody, anti-MHC Class I Antigen antibody |
| ProteinTarget: | HLA ABC |
| PackageSize: | 0.1 mg |
| GeneralRef: | General / background references:Neefjes JJ et al. A biochemical characterization of feline MHC products: unusually high expression of class II antigens on peripheral blood lymphocytes. Immunogenetics 23:341-7 (1986). Burrone OR & Milstein C Control of HLA-A,B,C synthesis and expression in interferon-treated cells. EMBO J 1:345-9 (1982). Brodsky FM & Parham P Evolution of HLA antigenic determinants: species cross-reactions of monoclonal antibodies. Immunogenetics 15:151-66 (1982). Barnstable CJ et al. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14:9-20 (1978). |
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