| Catalog Code: | NB110-17780 |
| Product Type: | Primary Antibody |
| Product Name: | Anterior Gradient 2 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 10551 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Anterior Gradient 2 |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse (88% identity with immunogen) and Cow (94% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | hAG-2 and hAG-3 are recently discovered human homologues of the secreted Xenopus laevis proteins XAG-1/2 (AGR-1/2) that are expressed in the cement gland, an ectodermal organ in the head associated with anteroposterior fate determination during early deve |
| Immunogen: | This antibody was developed against synthetic peptides corresponding to amino acids 55-72 (TQTYEEALYKSKTSNKPL) of human AGR2; Genbank accession no. NP_006399.1 |
| Localization: | Secreted |
| Specificity: | Researchers are encouraged to use the sequence and accession number that were used to design the peptide immunogen in order to assess potential cross-reactivity of the antibody to their species of interest. |
| Purity: | protein G purified |
| Buffer: | PBS containing 0.2% gelatin |
| Packaging: | 0.05 mg protein G purified Rabbit antisera. |
| Package Size: | 0.05 mg |
| Concentration: | 0.5 mg/ml |
| Application Summary: | ELISA, IHC-P |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| General References: | General / background references:Fletcher GC et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Br J Cancer |