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| Catalog Code: | NB100-94902 |
| Product Type: | Primary Antibody |
| Product Name: | CTSK Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 1513 (human) |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-CTSK |
| Cross Reactivity: | Human |
| Species Summary: | Hu(+) |
| Background: | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq] |
| Alternate Names: | anti-CTSK antibody, anti-cathepsin K antibody, anti-CTS02 antibody, anti-CTSO antibody, anti-CTSO1 antibody, anti-CTSO2 antibody, anti-MGC23107 antibody, anti-PKND antibody, anti-PYCD antibody, anti-cathepsin K (pycnodysostosis) antibody, anti-cathepsin O1 antibody, anti-cathepsin O2 antibody, anti-cathepsin X antibody |
| Immunogen: | Peptide with sequence C-KTHRKQYNNKVDE, from the internal region (near N-terminus) of the protein sequence according to NP_000387.1. |
| Epitope: | C-KTHRKQYNNKVDE |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Preservative: | 0.02% sodium azide |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 36kDa band observed in Human Lung and Human Ovary lysates (calculated MW of 37.0kDa according to NP_000387.1). Recommended concentration: 1-3ug/ml. |
| Application Summary: | ELISA 1:16000, Western Blot 1-3ug/ml, |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
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