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| Catalog Code: | NB100-93438 |
| Product Type: | Primary Antibody |
| Product Name: | SOX1 Antibody |
| List Price: | 195 |
| Clonality: | Polyclonal |
| Gene ID: | 6656 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-SOX1 |
| Cross Reactivity: | Human, Mouse |
| Species Summary: | Hu, Mu |
| Background: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq] |
| Alternate Names: | anti-SRY (sex determining region Y)-box 1 antibody, anti-SRY-related HMG-box gene 1 antibody |
| Immunogen: | Peptide with sequence C-AHPHNPQPMHR, from the internal region of the protein sequence according to NP_005977.2. |
| Epitope: | C-AHPHNPQPMHR |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Preservative: | 0.02% sodium azide |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Preliminary experiments gave an approx 26kDa band in lysates of cell line KELLY after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 39.0kDa according to NP_005977.2. The 26kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? |
| Application Summary: | ELISA 1:64000, Western Blot 0.3ug/ml, |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| General References: | Kan L, Israsena N, Zhang Z, et al. Sox1 acts through multiple independent pathways to promote neurogenesis. Dev Biol. 2004 May 15;269(2):580-94. PMID: 15110721 |
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