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| Catalog Code: | NB100-93397 |
| Product Type: | Primary Antibody |
| Product Name: | FZD4 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 8322 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-FZD4 |
| Cross Reactivity: | Human |
| Species Summary: | Hu(+) |
| Background: | This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq] |
| Alternate Names: | anti-FZD4 antibody, anti-frizzled homolog 4 (Drosophila) antibody, anti-EVR1 antibody, anti-FEVR antibody, anti-FZD4S antibody, anti-Fz-4 antibody, anti-FzE4 antibody, anti-GPCR antibody, anti-MGC34390 antibody, anti-WNT receptor frizzled-4 antibody, anti-exudative vitreoretinopathy 1 (autosomal dominant Criswick-Schepens syndrome) antibody, anti-frizzled 4 antibody |
| Immunogen: | Peptide with sequence DEEERRCDPIRIS, from the internal region of the protein sequence according to NP_036325.2. |
| Epitope: | DEEERRCDPIRIS |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Preservative: | 0.02% sodium azide |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 60kDa band observed in Human Colon and Small Intestine (Ileum) lysates (calculated MW of 59.9kDa according to NP_036325.2). Recommended concentration: 0.3-1ug/ml. |
| Application Summary: | ELISA 1:16000, Western Blot 0.3-1ug/ml, |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| General References: | You J, Nguyen AV, Albers CG, et al. Wnt Pathway-Related Gene Expression in Inflammatory Bowel Disease. Dig Dis Sci. 2007 Oct 16; [Epub ahead of print] PMID: 17939044 |
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