| request information: | |
| Catalog Code: | NB100-896 |
| Product Name: | Spinesin Antibody |
| Product Description: | Goat Polyclonal anti-Spinesin |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 80975 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide LDWIHDTAQDSLL, representing the C-Terminus of the human protein (residues 445-457) according to NP_110397 |
| Cross Reactivity: | Human, Mouse, Rat. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: experiments gave bands at approx 50kDa and 29kDa in Human Brain (Cerebral Cortex) lysates and in Mouse and Rat Brain lysates after 0.5µg/ml antibody staining. These bands correspond to earlier findings in literature with different antibodies (Yamaguchi et al, J Biol Chem. 2002 Mar 1;277(9):6806-12; PMID: 11741986). This protein has a calculated MW of 49.6kDa according to NP_110397.1. Recommended concentration: 0.5-1.5µg/ml. |
| Background: | Spinesin is a protein that belongs to the serine protease family which has been known to be involved in many physiological and pathological processes. Spinesin has been shown to be expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-Transmembrane protease serine 5 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| Notes Main: | Principal Names - TMPRSS5; transmembrane protease, serine 5 (spinesin); SPINESIN; spinesin. Official Gene Symbol - TMPRSS5. GenBank Accession Number ? NP_110397. LocusLink ID - 80975 |
| General References: | Yamaguchi N et al. Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. J Biol Chem 277:6806-12 (2002). |
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