| Catalog Code: | NB100-895 |
| Product Type: | Primary Antibody |
| Product Name: | VAV2 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 7410 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-VAV2 |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse due to sequence homology. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively di |
| Alternate Names: | anti-VAV2 oncogene antibody |
| Immunogen: | Synthetic peptide: ETEAKYYRTLEDIEC, from the internal region of the human protein (residues 208-221) according to NP_003362. |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, detects a band of approximately 100 kDa (predicted molecular weight: 100 kDa). Not tested in other applications. Recommended Starting Dilution:* ELISA (peptide): 1/32000 WB: 1 - 1.5 u |
| Application Summary: | WB, ELISA |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| General References: | Henske EP et al. Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1. Ann Hum Genet 59 ( Pt 1):25-37 (1995). |
| Notes Main: | GenBank Accession Number ? NP_003362.LocusLink ID - 7410 (human); 22325 (mouse).Gene Ontology terms - guanyl-nucleotide exchange factor activity; intracellular signaling cascade; diacylglycerol binding. |