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| Catalog Code: | NB100-87027 |
| Product Name: | BRAF Antibody |
| Product Description: | Rabbit Polyclonal anti-BRAF |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene ID: | 673 |
| Reference Sequence: | NP_004324.2 |
| Concentration: | 0.2 mg/ml |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 25 and 75 of human v-raf murine sarcoma viral oncogene homolog B1 using the numbering given in entry NP_004324.2 (GeneID 673). |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for western blot and immunoprecipitation. |
| Background: | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq] |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| Application Summary: | Western Blot 1:2000-1:10000, immunoprecipitation 2-5 mcg/mg lysate |
| Species Summary: | Hu |
| Alternate Names: | anti-RAF antibody, anti-b-RAF antibody, anti-BRAF1 antibody, anti-b-RAF1 antibody, anti-RAFB1 antibody, anti-v-raf murine sarcoma viral oncogene homolog B1 antibody |
| Package Size: | 0.02 mg |
| Preservative: | 0.09% Sodium Azide |
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more information: | company product webpage |