| request information: | |
| Catalog Code: | NB100-863 |
| Product Name: | DAPK 2 Antibody |
| Product Description: | Goat Polyclonal anti-DAPK 2 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 23604 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence KALHPRRRSSTS, representing the C-Terminus of the protein (residues 359-370) according to NP_055141. |
| Cross Reactivity: | Cross-reacts with Mouse. Expected to cross-react with Human due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where a 40-45kDa band is seen in Mouse Brain extracts.Recommended Starting Dilutions*:WB: 1-3ug/ml*Optimal dilutions shoudl be determined by the end user. |
| Background: | This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Mu |
| Alternate Names: | anti-DAK2 antibody, anti-DAP Kinase Related Protein 1 antibody, anti-DAPK2 antibody, anti-Death Associated Protein Kinase 2 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| Notes Main: | LocusLink ID - 23604 |
| General References: | Kawai T et al. Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity. Oncogene 18:3471-80 (1999). |
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