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| Catalog Code: | NB100-853 |
| Product Name: | PLRG1 Antibody |
| Product Description: | Goat Polyclonal anti-PLRG1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 5356 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence PVSWKPEIIKRKRF, representing the C-Terminus of the protein (residues 501-514) according to NP_002660. |
| Cross Reactivity: | Cross-reacts with Mouse. Expected to cross-react with Human and Rat due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where a 60kDa band is seen in Mouse Kidney extracts. Recommended Starting Dilutions*:WB: 0.5-2ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | PLRG1 is a spliceosomal protein that is highly conserved across species. PLRG1 has been shown to be part of sub-spliceosomal protein complexes that are essential for pre-mRNA splicing in both yeast and humans. PLRG1 and CDC5L interact directly in vitro. This interaction is mediated by WD40 regions in PLRG1 and the C-terminal domain of CDC5L. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Mu |
| Alternate Names: | anti-Pleiotropic Regulator 1 antibody, anti-PRL1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Nacmeth K et al. Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis. Genes Dev 12:3059-73 (1998). |
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