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| Catalog Code: | NB100-845 |
| Product Name: | PPP2R5E Antibody |
| Product Description: | Goat Polyclonal anti-PPP2R5E |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 5529 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence LKRGLRRDGIIPT, representing the C-Terminus of the protein (residues 455-467) according to NP_006237. |
| Cross Reactivity: | Cross-reacts with Mouse. Expected to cross-react with Human due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where 55kDa and 40kDa bands are seen in Mouse Brain extracts. Please note that the two bands may correspond to two different isoforms. Two isoforms of the epsilon mRNA have been detected in Northern blots (J Biol Chem. 271(36):22081-9, 1996.Recommended Starting Dilutions*:WB: 0.5-2ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Mu |
| Alternate Names: | anti-Regulatory subunit B of protein phosphatase 2 epsilon isoform antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | McCright B & Virshup DM Identification of a new family of protein phosphatase 2A regulatory subunits. J Biol Chem 270:26123-8 (1995). |
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