| CatalogCode: | NB100-843 |
| ProductName: | ARFGAP 1 Antibody |
| Product Description: | Goat Polyclonal anti-ARFGAP 1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide with sequence NGVVTSIQDRYGS, representing the C-Terminus of the protein (residues 504-516) according to NP_055385. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where a 55-60kDa band is seen in Mouse Brain extracts. Recommended Starting Dilutions*:WB: 1.0-3.0ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which is thought to interact with ADP-ribosylation factor 1 (ARF1). The encoded protein likely promotes hydrolysis of ARF1-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-ADP ribosylation factor GTPase activating protein 1 antibody, anti-ARFGAP3 antibody |
| ProteinTarget: | ARFGAP 1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Liu X et al. Functional characterization of novel human ARFGAP3. FEBS Lett 490:79-83 (2001). |
| NotesMain: | LocusLink ID: 26286 |
| Gene_Id: | 26286 |
| Omim_ID: | NB100-55257 |