| request information: | |
| Catalog Code: | NB100-840 |
| Product Name: | FGR Antibody |
| Product Description: | Goat Polyclonal anti-FGR |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 2268 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence TSAEPQYQPGDQT representing the C-terminus of the human protein (residues 517-529) according to NP_005239. |
| Cross Reactivity: | Cross-reacts with Mouse. Expected to cross-react with Human due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for Western Blot where a 55-60kDa band is seen in Mouse Spleen extracts.Recommended Starting Dilutions*:WB: 0.5-2ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | Fgr is a member of the Src family of non-receptor tyrosine kinases. It is expressed in neutrophils, monocytes, macrophages and natural killer cells. Expression of Fgr is developmentally regulated and required in normal myelomonocytic differentiation in vivo. HL-60 cells induced to differentiate with retinoic acid express high levels of Fgr. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Mu |
| Alternate Names: | anti-Gardner-Rasheed feline sarcoma viral (v-fgr) antibody, anti-SRC2 antibody, anti-c-fgr antibody, anti-p55c-fgr antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Katamine S et al. Primary structure of the human fgr proto-oncogene product p55c-fgr. Mol Cell Biol 8:259-66 (1988). |
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