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| Catalog Code: | NB100-828 |
| Product Name: | DOCK 1 Antibody |
| Product Description: | Goat Polyclonal anti-DOCK 1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 1793 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence TTRKQTSVDSGIVQ, representing the C-Terminus of the human protein (residues 1852-1865) according to NP_001371. |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where a 150-200kDa band is seen in A431 cell lysate.Recommended Starting Dilutions*:WB: 3-4ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-Dedicator of Cytokinesis 1 antibody, anti-DOCK180 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Hasegawa H et al. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol 16:1770-6 (1996). |
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