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| Catalog Code: | NB100-82147 |
| Product Name: | PKCzeta Antibody |
| Product Description: | Rabbit Polyclonal anti-PKCzeta |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Reference Sequence: | Q05513 |
| Immunogen: | The antiserum was produced against synthesized non-phosphopeptide derived from human PKC around the phosphorylation site of threonine 410( T-S-TP-F-C). |
| Specificity: | PKC (specific to a.a. 410) antibody detects endogenous levels of total PKC protein. |
| Cross Reactivity: | This antibody is reactive against Human, Mouse, Rat |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for:immunohistochemistry 1:50-1:100 |
| Background: | Protein Kinase C (PKC) isoforms are serine/threonine kinases involved in signal transduction pathways that govern a wide range of physiological processes including differentiation, proliferation, gene expression, brain function, membrane transport and the organization of cytoskeletal and extracellular matrix proteins. Increasing evidence from studies using in vitro and in vivo systems points to PKC as a key regulator of critical cell cycle transitions, including cell cycle entry and exit and the G1 and G2 checkpoints. PKC-mediated control of these transitions can be negative or positive, depending on the timing of PKC activation during the cell cycle and on the specific PKC isozymes involved. There have been at least 12 different PKC isoforms identified in humans to date, including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol. |
| Application Summary: | immunohistochemistry 1:50-1:100, |
| Species Summary: | Hu, Mu, Rt |
| Alternate Names: | anti- nPKC epsilon antibody, anti-AAG6 antibody, anti-Aging associated gene 6 antibody, anti-kinase PKC alpha antibody, anti-MGC129900 antibody, anti-MGC129901 antibody, anti-MGC41878 antibody, anti-MGC57564 antibody, anti-PKC A antibody, anti-PKC alpha antibody, anti-PKC B antibody, anti-PKC beta antibody, anti-PKC delta antibody, anti-PKC epsilon antibody, anti-PKC G antibody, anti-PKC gamma antibody, anti-PKCA antibody, anti-PKCB antibody, anti-PKCC antibody, anti-PKCEA antibody, anti-PKCG antibody, anti-PRKACA antibody, anti-PRKC A antibody, anti-PRKC G antibody, anti-PRKCA antibody, anti-PRKCB antibody, anti-PRKCB1 antibody, anti-PRKCB2 antibody, anti-PRKCD antibody, anti-PRKCG antibody, anti-Protein kinase C alpha antibody, anti-Protein kinase C alpha type antibody, anti-Protein Kinase C antibody, anti-Protein kinase C beta 1 antibody, anti-Protein kinase C beta 1 polypeptide antibody, anti-Protein kinase C beta type antibody, anti-Protein kinase C gamma antibody, anti-Protein kinase C gamma type antibody, anti-Protein kinase C zeta antibody, anti-SCA14 antibody, anti-Spinocerebellar ataxia 14 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Sodium Azide |
| Notes Main: | Kinase/Phosphatases,NF-kappa B,Insulin/Glucose |
| General References: | Parmentier JH, et al. (2004) BMC Cell Biol; 5: 4. Castrillo A, et al. (2003) Mol Cell Biol; 23(4): 1196-1208. Paramio JM, et al. ( 2001) Mol Cell Biol; 21(21): 7449-7459. Braiman L, et al. (2001) Mol Cell Biol; 21(22): 7852-7861. |
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