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| Catalog Code: | NB100-821 |
| Product Name: | PRAM1 Antibody |
| Product Description: | Goat Polyclonal anti-PRAM1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 84106 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide: DFCDPLENQPLPLGR. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Western Blot: Approx 90-100kDa band seen in Jurkat cell lysates. Recommended for use at 1-3ug/ml. Overnight incubation is recommended with this antibody. Please note that although the predicted MW of PRAM-1 is 79kDa, Moog-Lutz et al., (J. Biol. Chem, Jun 2001; 276: 22375 - 22381) detected aPRAM-1 migrating with an apparent molecular mass of 97kDa and this is what we observed as well. |
| Background: | PRAM-1 is an adaptor protein interacting with proteins involved in an ATRA-signaling pathway |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-PRAM-1 antibody, anti-PRAM-1 protein antibody, anti-PML-RARA target gene encoding an Adaptor Molecule-1 antibody, anti-Official Symbol antibody, anti-PRAM-1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Moog-Lutz C et al. PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells. J Biol Chem 276:22375-81 (2001). |
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