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| Catalog Code: | NB100-81821 |
| Product Name: | beta-Catenin Antibody |
| Product Description: | Rabbit Polyclonal anti-beta-Catenin |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Immunogen: | The antiserum was produced against synthesized non-phosphopeptide derived from human -Catenin around the phosphorylation site of threonine 41/serine 45 (A-T-TP-T-A-P-SP-L-S). |
| Cross Reactivity: | This antibody is reactive against Human, Mouse, Rat |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for:Western Blot 1:500-1:1000 |
| Background: | The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol. |
| Application Summary: | Western Blot 1:500-1:1000, |
| Species Summary: | Hu, Mu, Rt |
| Alternate Names: | anti-Beta catenin antibody, anti-Cadherin associated protein antibody, anti-Catenin beta 1 antibody, anti-CATNB antibody, anti-CTNNB antibody, anti-CTNNB1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Sodium Azide |
| Notes Main: | Wnt/beta-catenin |
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more information: | company product webpage |