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| Catalog Code: | NB100-818 |
| Product Name: | MADH 4 Antibody |
| Product Description: | Goat Polyclonal anti-MADH 4 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 4089 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence HTMPIADPQPLD representing the C-Terminus of the protein (residues 541-552) according to NP_005350. |
| Cross Reactivity: | Cross-reacts with Mouse. Expected to cross-react with Human and Rat due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where a 75-80kDa band is seen in A431 cell lysate. Recommended Starting Dilutions*:WB: 0.5-2ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | MADH4 is a common mediator of signal transduction by the TGF-beta (transforming growth factor) superfamily; it may act as a tumor suppressor. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Mu |
| Alternate Names: | anti-DPC4 antibody, anti-JIP antibody, anti-Mothers against decapentaplegic homolog 4 antibody, anti-SMAD4 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Kim SK et al. DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. Cancer Res 56:2519-21 (1996). |
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