| CatalogCode: | NB100-816 |
| ProductName: | MADH 2 Antibody |
| Product Description: | Goat Polyclonal anti-MADH 2 |
| Clonality: | Polyclonal |
| Immunogen: | Peptide with sequence SEIWGLSTPNTID, from Internal of the protein sequence according to NP_005892 |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Western Blot ? Approx. 45kDa and 50kDa band seen in HeLa lysates. Recommended for use at 1.0-3.0ug/ml. |
| Background: | MADH2 (SMAD2) is a transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. MADH2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-MADH2 antibody, anti-JV18 antibody, anti-MADR2 antibody, anti-SMAD2 antibody, anti-JV18-1 antibody, anti-MAD antibody, anti-mothers against decapentaplegic homolog 2 (Drosophila) antibody, anti-Mothers against decapentaplegic antibody, anti-Drosophila antibody, anti-homolog of 2 antibody, anti-MAD (mothers against decapentaplegic antibody, anti-Drosophila) homolog 2 antibody, anti-Official Symbol antibody, anti-MADH2 antibody |
| ProteinTarget: | MADH 2 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Eppert K et al. MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86:543-52 (1996). |
| NotesMain: | Principal Names: MADH2 (mothers against decapentaplegic homolog 2), JV18, MADR2, SMAD2, JV18-1. Official Gene Symbol: MADH2GenBank Accession Number: NP005892 LocusLink ID: 4087 |
| Gene_Id: | 4087 |
| Omim_ID: | NB100-818 |
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