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| Catalog Code: | NB100-81030 |
| Product Name: | HCN1 Antibody |
| Product Description: | Rabbit Polyclonal anti-HCN1 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Immunogen: | Synthetic peptide derived from C-terminal domain of HCN1 protein |
| Specificity: | Antiserum reacts specifically with human 99 kDa protein |
| Cross Reactivity: | Cross reacts with HCN1 protein from mouse, rat and other species |
| Packaging: | 0.2 ml Whole Rabbit Ascites |
| Uses: | Optimal dilution should be determined by the end userThe following are guidelines only :- Immunohistochemistry : 1/200 to 1/1 000- Western Blot : 1/500 to 1/5 000 |
| Background: | Hyperpolarization activated cation channels of the HCN gene family such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain. HCN1 is a member of a family of pacemaker channels activated by hyperpolarisation and regulated by cyclic nucleotides. HCN1 and HCN2 play an important role for motor learning and neuronal integration by cerebellar Purkinje cells; as well as, shaping autonomous activity of single neurons and the periodicity of network oscillations. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Whole antisera |
| Host Name: | Rabbit |
| Application Summary: | immunohistochemistry 1:200-1:1000, Western Blot 1:500-1:5000 |
| Species Summary: | Mu, Rt(-) |
| Package Size: | 0.2 ml |
| Preservative: | No Preservative |
| Notes Main: | Lyophilized powder (glass vial) - Vial must be reconstituted in 0.2 ml of distillated water |
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