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| Catalog Code: | NB100-80898 |
| Product Name: | Myosin Light Chain 2 Antibody |
| Product Description: | Rabbit Polyclonal anti-Myosin Light Chain 2 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene Symbol: | MYL2 |
| Reference Sequence: | P10916 |
| Immunogen: | Synthetic peptide; Amino acids surrounding Ser 18 of human MYL2 |
| Cross Reactivity: | This antibody is reactive against Human, Mouse, Rat |
| Packaging: | 0.05 mg Immunogen affinity purified Rabbit antisera |
| Uses: | This antibody is useful for IHC 10 ug/ml, WB |
| Background: | Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each ~200,000 daltons, and four light chains each ~16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. Human myosin light chain has clinical application as a cardiac marker. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS, 50% glycerol |
| Application Summary: | immunohistochemistry 10 ug/ml, Western Blot, |
| Species Summary: | Hu, Mu, Rt |
| Alternate Names: | anti-MYL2 antibody, anti-CMH10 antibody, anti-DKFZP779C0562 antibody, anti-MLC-2 antibody, anti-MLC-2V antibody, anti-MLC2 antibody, anti-Cardiac Ventricular Myosin Light Chain-2 antibody |
| Package Size: | 0.05 mg |
| Preservative: | 0.02% sodium azide |
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more information: | company product webpage |