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| Catalog Code: | NB100-80845 |
| Product Name: | Toll-like Receptor 8 Antibody |
| Product Description: | Rabbit Polyclonal anti-Toll-like Receptor 8 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene Symbol: | TLR8 |
| Reference Sequence: | Q9NR97 |
| Immunogen: | Synthetic peptide; peptide corresponding to 16 amino acids near the middle of human TLR8 |
| Cross Reactivity: | This antibody is reactive against Human, Mouse |
| Packaging: | 0.05 mg Affinity purified Rabbit antisera |
| Uses: | This antibody is useful for ICC, IHC 5 ug/ml, WB 0.5 ug/ml 2 ug/ml |
| Background: | The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Host Name: | Rabbit |
| Buffer: | Phosphate buffered saline |
| Application Summary: | Immunocytochemistry, immunohistochemistry 5 ug/ml, Western Blot 0.5-2 ug/ml, |
| Species Summary: | Hu, Mu |
| Alternate Names: | anti-TLR8 antibody, anti-MGC119599 antibody, anti-MGC119600 antibody |
| Package Size: | 0.05 mg |
| Preservative: | 0.02% sodium azide |
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more information: | company product webpage |