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| Catalog Code: | NB100-80844 |
| Product Name: | Toll-like Receptor 7 Antibody |
| Product Description: | Rabbit Polyclonal anti-Toll-like Receptor 7 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene Symbol: | TLR7 |
| Reference Sequence: | Q9NYK1 |
| Concentration: | 1 mg/ml |
| Immunogen: | Synthetic peptide; peptide corresponding to 14 amino acids near the middle of mouse TLR7 |
| Cross Reactivity: | This antibody is reactive against Human, Mouse |
| Packaging: | 0.05 mg Affinity purified Rabbit antisera |
| Uses: | This antibody is useful for ICC, IHC 5 ug/ml, WB 0.5 ug/ml 2 ug/ml |
| Background: | The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL 1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1 10) have been described. Stimulation of the NFkB signaling pathway by TLR7 suggests that it plays a role in immune response. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host Name: | Rabbit |
| Buffer: | Phosphate buffered saline |
| Application Summary: | Immunocytochemistry, immunohistochemistry 5 ug/ml, Western Blot 0.5-2 ug/ml, |
| Species Summary: | Hu, Mu |
| Alternate Names: | anti-TLR7 antibody |
| Package Size: | 0.05 mg |
| Preservative: | 0.02% sodium azide |
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more information: | company product webpage |