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| Catalog Code: | NB100-807 |
| Product Name: | ITK Antibody |
| Product Description: | Goat Polyclonal anti-ITK |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 3702 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Peptide with sequence RLLRQLAEIAESGL, from C-Terminus of the protein sequence according to NP_005537 |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | In Western blot assays a band of approx 75 kDa is seen in Jurkat Lysates. Recommended for use at 0.5-2 ug/ml. |
| Localization: | Plasma membrane |
| Background: | This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-Principal Names antibody, anti-ITK antibody, anti-EMT antibody, anti-LYK antibody, anti-PSCTK2 antibody, anti-IL2-inducible T-cell kinase antibody, anti-tyrosine-protein kinase LYK antibody, anti-homolog of mouse T-cell itk/tsk antibody, anti-tyrosine-protein kinase ITK/TSK antibody, anti-Official Symbol antibody, anti-ITK antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Tanaka N et al. A novel human tyrosine kinase gene inducible in T cells by interleukin 2. FEBS Lett 324:1-5 (1993). |
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