| CatalogCode: | NB100-806 |
| ProductName: | SHP2 Antibody |
| Product Description: | Goat Polyclonal anti-SHP2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide with sequence YENVGLMQQQKSFR representing the C-terminus of the human protein (residues 580-593), according to NP_002825. |
| CrossReactivity: | Cross-reacts with Human. Expected to cross-react with Mouse and Rat due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be sued in Western Blot where a 70 kDa band is seen in 293 and Human nuscle cell lysate (predicted MW of 68 kDa. Not tested in other applications.Recommended Starting Dilutions*:WB: 1-3 ug/ml*Optimal dilutions should be determined by the end user. |
| Control: | Human muscle and 293 lysate. |
| Background: | A protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-BPTP3 antibody, anti-CFC antibody, anti-Noonan syndrome 1 protein tyrosine phosphatase 2C antibody, anti-NS1 antibody, anti-Protein Tyrosine Phosphatase Non receptor Type 11 antibody, anti-PTP1D antibody, anti-PTP2C antibody, anti-PTPN11 antibody, anti-SAP2 antibody, anti-SH2 domain containing protein tyrosine phosphatase 2 antibody, anti-SHPTP2 antibody, anti-SHPTP3 antibody, anti-SIT protein precursor antibody |
| ProteinTarget: | SHP2 antibody |
| PackageSize: | 0.1 mg |
| GeneralRef: | Tartaglia M et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet 29:465-8 (2001). Saxton TM et al. The SH2 tyrosine phosphatase shp2 is required for mammalian limb development. Nat Genet 24:420-3 (2000). |
| Gene_Id: | 5781 |
| Omim_ID: | NB100-75307 |
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