| request information: |
|
| Catalog Code: | NB100-79909 |
| Product Name: | Casein Kinase II Antibody |
| Product Description: | Rabbit Monoclonal anti-Casein Kinase II (EP1963Y) |
| Clone: | EP1963Y |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Reference Sequence: | P68400 |
| Immunogen: | A synthetic peptide corresponding to residues near the N-terminal of human CKII protein was used as an immunogen. |
| Epitope: | (alpha subunit) |
| Specificity: | A synthetic peptide corresponding to residues near the N-terminal of human CKII protein was used as an immunogen. |
| Cross Reactivity: | This antibody is reactive against Human, Mouse, Rat |
| Packaging: | 0.1 ml Rabbit ascites |
| Uses: | This antibody is useful for: Western Blot, immunohistochemistry, flow cytometry / FACS analysis |
| Background: | Casein Kinase II (CKII, CK2, phosvitin kinase, troponin T kinase, casein kinase G) is a ubiquitous serine/threonine protein kinase that is highly conserved and commonly found in eukaryotic cells (found in the cytoplasm and the nucleus). CKII is a heterotertamer that consists of two catalytic subunits (alpha, alpha-prime) and two regulatory beta subunits (1). CKII can utilize both GTP and ATP as the phosphate donor and phosphorylates threonine and serine residues. Therefore, CKII is a multifunctional protein kinase with broad range of substrates (e.g. c-Myc, c-Myb, c-Fos, c-Jun, p53, Rb, HPVE7) and it has been implicated in various cell functions/processes from cell transformation to mitosis. (2) |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Application Summary: | Western Blot 1:500-1000, immunohistochemistry 1:50-100, flow cytometry / FACS analysis 1:20 |
| Species Summary: | Hu, Mu, Rt |
| Alternate Names: | Anti-CK II antibody |
| Package Size: | 0.1 ml |
| General References: | 1. Jakobi R. et al. Europ. J. Biochem. 183: 227-233, 1989. 2. Donella-Deana A. et al. Biochem J., 357:563-567, 2001. |
order or
more information: | company product webpage |
|