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| Catalog Code: | NB100-79866 |
| Product Name: | NLGN3 Antibody |
| Product Description: | Goat Polyclonal anti-Neuroligin 3 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 54413 (human) |
| Gene Symbol: | NLGN3 |
| Reference Sequence: | NP_061850.2 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide, C-RKDKRRQEPLRQPS, representing the internal region of the sequence according to NP_061850.2 |
| Epitope: | RKDKRRQEPLRQPS |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 85-90kDa band observed in Human Brain (Amygdala) lysates (calculated MW of 91.6kDa according to NP_061850.2). Recommended concentration: 0.05-0.2ug/ml. |
| Background: | This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but their full length sequences have not been determined. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Application Summary: | ELISA 1:16000, Western Blot 0.05-0.2ug/ml |
| Species Summary: | Hu |
| Alternate Names: | anti-LGN3 antibody, anti-neuroligin 3 antibody, anti-ASPGX1 antibody, anti-AUTSX1 antibody, anti-HNL3 antibody, anti-KIAA1480 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Sodium Azide |
| Homology: | Human, Mouse, Rat, Dog |
| General References: | Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Sudhof TC. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science. 2007 Oct 5;318(5847):71-6. Epub 2007 Sep 6. PMID: 17823315 |
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more information: | company product webpage |