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| Catalog Code: | NB100-79774 |
| Product Name: | HP1-beta Antibody |
| Product Description: | Goat Polyclonal anti-HP1-beta |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene ID: | 10951 |
| Reference Sequence: | NP_006798.1 |
| Concentration: | 1 mg/ml |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 50 and 100 of human Heterochromatin Protein p25 beta (Chromobox Homolog 1) using the numbering given in entry NP_006798.1 (GeneID 10951). |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Goat antisera. |
| Uses: | This antibody is useful for western blot. It is not recommended for immunoprecipitation. |
| Background: | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| Application Summary: | Western Blot 1:1000-1:5000 |
| Species Summary: | Hu |
| Alternate Names: | anti-CBX1 antibody, anti-Chromobox homolog 1, HP1Hs-beta antibody, anti-Heterochromatin protein 1 beta, MOD1 antibody, anti-Modifier 1 protein, Heterochromatin protein p25, M31 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.1% Sodium Azide |
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more information: | company product webpage |