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| Catalog Code: | NB100-796 |
| Product Name: | ORC 3L Antibody |
| Product Description: | Goat Polyclonal anti-ORC 3L |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 23595 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide with sequence QKTDHVARLTWGGC, representing the C-Terminus of the human protein (residues 698-711) according to NP_036513. |
| Cross Reactivity: | Cross-reacts with Human, Mouse, Rat, Dog. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where 80kDa and 35KDa bands are seen in HeLa cell lysates. The 35kDa band could be cell/tissue specific. For example, Thome et al., [J. Biol. Chem, Nov 2000; 275: 35233 - 35241] observed that brain expressed a 40-45-kDa protein that reacted strongly with the anti-Orc3 antibody. Moreover, splice prediction software (http://www.bioinformatics.ucla.edu/ASAP/) indicated the possibility of a shorter isoform. Recommended Starting Dilutions*:Western Blot: 0.5-2 ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | ORC3L is involved in DNA replication origin binding. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot 0.5-2 ug/ml |
| Species Summary: | Ca, Hu, Mu, Rt |
| Alternate Names: | anti-Homolog of Latheo antibody, anti-Origin Recognition Complex Subunit 3 Isoform 1 antibody, anti-LAT antibody, anti-ORC3 antibody, anti-LATHEO antibody, anti-IMAGE50150 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Pinto S et al. latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant. Neuron 23:45-54 (1999). PUBMED:10402192 |
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