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| Catalog Code: | NB100-78617 |
| Product Name: | S-100 Antibody |
| Product Description: | Rabbit Polyclonal anti-S-100 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 10 mg/ml |
| Immunogen: | Bovine brain S-100 protein |
| Cross Reactivity: | Unknown. |
| Packaging: | 0.1 ml of IgG purified Rabbit antisera |
| Localization: | Cytoplasmic and nuclear |
| Background: | S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Host Name: | Rabbit |
| Buffer: | Phosphate-buffered saline |
| Application Summary: | ELISA |
| Alternate Names: | anti-Bpb antibody, anti-NEF antibody, anti-S 100 protein alpha chain antibody, anti-S 100 PROTEIN BETA CHAIN antibody, anti-S 100 protein beta subunit antibody, anti-S100 alpha antibody, anti-S100 beta antibody, anti-S100 calcium binding protein A1 antibody, anti-S100 calcium binding protein B antibody, anti-S100 calcium binding protein beta neural antibody, anti-S100 protein alpha chain antibody, anti-S100 protein alpha polypeptide antibody, anti-S100 protein beta polypeptide neural antibody, anti-S100A antibody, anti-S100a1 antibody, anti-S100B antibody, anti-S100beta antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.1% sodium azide |
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