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| Catalog Code: | NB100-78586 |
| Product Name: | ALDH1A1 Antibody |
| Product Description: | Rabbit Polyclonal anti-ALDH1A1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 216 |
| Concentration: | 1 mg/ml |
| Immunogen: | Synthetic peptide - Containing amino acids between 400-550. |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg of peptide affinity purified Rabbit antisera |
| Uses: | Suggested starting dilutions are as follows. WB: 1:2,000-1:10,000. |
| Localization: | Cytoplasmic |
| Background: | ALDH1A (Aldehyde dehydrogenases class 1 alpha is belongs to a group of enzymes that catalyse the dehydrogenation of aldehydes. All of this enzymes exist mitochondria and endoplasmic reticulum. Aldehyde dehydrogenases have a broad substrate specificity. Oxidation of aldehydes is considered to be generally a detoxification reaction, removing the electrophilic products of alcohol oxidation. ALDH1A1 is an aldehyde dehydrogenase able to oxidize a wide variety of aliphatic aldehydes (retinaldehyde, acetaldehyde, etc.) to the corresponding carboxylic acids (retinoic acid, acetic acid, etc.). ALDH1A1 (also known as RALDH1, ALDH1, or AHD2) is highly expressed in the dorsal retina, ventral midbrain (dopaminergic neurons), and hematopoietic stem cells. ALDH1A1 is involved in retinoic acid (RA) synthesis during vertebrate embryogenesis. ALDH1A1 is first detected at E9.0-E10.5 in cranial tissues (ventral mesencephalon, dorsal retina, thymic primordia, optic vesicles) and in the mesonephros. ALDH1A1 is also of interest in Parkinson's Disease (PD) being expressed in the the A9 dopaminergic (DA) neuronal group projecting to the dorsal striatum; this is the most vulnerable site in PD (Chung et al, 2005). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | peptide affinity purified |
| Host Name: | Rabbit |
| Buffer: | Phosphate-buffered saline, pH 7.2 |
| Application Summary: | Western Blot 1:2,000-1:10,000 |
| Species Summary: | Hu |
| Alternate Names: | anti-Acetaldehyde dehydrogenase 1 antibody, anti-AHD2 antibody, anti-ALDC antibody, anti-Aldehyde dehydrogenase 1 family member A1 antibody, anti-Aldehyde dehydrogenase 1 soluble antibody, anti-Aldehyde dehydrogenase 1A1 antibody, anti-Aldehyde Dehydrogenase antibody, anti-Aldehyde dehydrogenase cytosolic antibody, anti-Aldehyde dehydrogenase family 1 member A1 antibody, anti-Aldehyde dehydrogenase liver cytosolic antibody, anti-ALDH 1 antibody, anti-ALDH 1A1 antibody, anti ALDH class 1 antibody, anti-ALDH-E1 antibody, anti-ALDH1 A1 antibody, anti-ALDH1 antibody, anti-ALDH11 antibody, anti-ALHDII antibody, anti-MGC2318 antibody, anti-PUMB1 antibody, anti-RALDH 1 antibody, anti-RalDH1 antibody, anti-Retinal dehydrogenase 1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.01% thimerosal |
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