| CatalogCode: | NB100-78581 |
| ProductName: | NuMA Antibody |
| Product Description: | Mouse Monoclonal anti-NuMA (SPM300) |
| Clone: | SPM300 |
| Clonality: | Monoclonal |
| Immunogen: | Colon carcinoma Ls174T cells |
| Epitope: | Resistant to phosphatases |
| CrossReactivity: | Human. |
| Packaging: | 0.05 mg of Affinity purified Mouse antisera |
| Localization: | Nuclear/Cytoplasmic |
| Control: | Human tonsil, SW156 cells |
| Background: | NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200kDa during apoptosis. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Isotype: | IgM kappa |
| Host_Name: | Mouse |
| Buffer: | Phosphate-buffered saline, pH 7.2, containing 0.2% BSA |
| ListPrice: | 325 |
| AppSummary: | IF, IHC-P, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Centrophilin stabilizes mitotic spindle in mitotic cells antibody, anti-Nuclear mitotic apparatus protein 1 antibody, anti-Nuclear mitotic apparatus protein antibody, anti-NUMA 1 antibody, anti-NuMA protein antibody, anti-NUMA1 antibody, anti-SP H antigen antibody, anti-Structural nuclear protein antibody |
| ProteinTarget: | NuMA |
| PackageSize: | 0.05 mg |