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| Catalog Code: | NB100-78579 |
| Product Name: | Keratin 19 Antibody |
| Product Description: | Mouse Monoclonal anti-Keratin 19 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Detergent-insoluble extract of human mammary epithelial organoids |
| Cross Reactivity: | Unknown. |
| Packaging: | 0.1 ml of Protein A purified Mouse antisera |
| Localization: | Cytoplasmic |
| Background: | The degree of keratin 19 in breast cancer distinguishes malignant from benign tumors. This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered saline |
| Application Summary: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-CK 19 antibody, anti-ck19 antibody, anti-Cytokeratin 19 antibody, anti-k19 antibody, anti-k1cs antibody, anti-Keratin 19 antibody, anti-Keratin type i 40kD antibody, anti-Keratin type I cytoskeletal 19 antibody, anti-krt19 antibody, anti-mgc15366 antibody |
| Package Size: | 0.1 ml |
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more information: | company product webpage |