| CatalogCode: | NB100-78565 |
| ProductName: | NEK9 Antibody |
| Product Description: | Rabbit Polyclonal anti-NEK9 [Thr210] |
| Clonality: | Polyclonal |
| Immunogen: | Modified peptide |
| CrossReactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated. |
| Control: | Cytoplasm |
| Background: | NEK9 is a 107 kD member of the serine/threonine-protein kinase family, NIMA subfamily containing a coiled-coil domain, and RCC1 repeats. This cytoplasmic protein forms dimers and is a pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation, Nek9 is activated during mitosis by intramolecular autophosphorylation at Thr210. Nek9 has been shown to interact with Ran GTPase (greater affinity for Ran-GDP over Ran-GTP), NEK6, NEK7, BICD2, histone H3, myelin basic protein, and beta-casein. The poly6360 antibody recognizes human phospho-NEK9 (Thr210) and has been shown to be useful for immunoflorence staining. This antibody does not detect NEK9 phosphorylated at other sites. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | 325 |
| AppSummary: | IF |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Serine/Threonine-protein kinase Nek9 antibody, anti-NimA-related protein kinase 9 antibody |
| ProteinTarget: | NEK9 |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Holland, P., et al., 2002. J. Biol. Chem. 277:16229. 2. Roig, J., et al., 2002. Genes Dev. 16:1640. 3. Belham, C., et al., 2003. J. Biol. Chem. 278:34897. |
| Phosphorylated: | Thr210 |
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