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| Catalog Code: | NB100-78542 |
| Product Name: | Cyclin B1 Antibody |
| Product Description: | Rabbit Polyclonal anti-Cyclin B1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Peptide mapping to the carboxy terminus of human cyclin B1 |
| Cross Reactivity: | Human, Mouse, Rat. |
| Packaging: | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. nbsp Western blotting suggested working dilution(s): Use nbsp10 microliter per 5 ml antibody dilution buffer for each mini-gel. nbsp Immunohistochemistry. It is recommended that the reagent be titrated for optimal performance for each application. nbsp |
| Background: | Cyclin B1 belongs to the cyclin family, Cyclin AB subfamily, and predicted molecular weight 48 kD. Cyclin B1 is expressed ubiquitously in all eukaryotes and the level of cyclin B1 was minimal in G, began to rise in S phase, and is primarily cytoplasmic. Cyclin B1 moves into the nucleus just at the start of mitosis and associates with condensed chromosomes and the mitotic spindle. The level of cyclin B1 peaked at the G/M transition. Cyclin B1 is essential for the control of the cell cycle at the G2/M transition. The poly6334 antibody has been shown to be useful for western blotting and immunohistochemistry of human, mouse, and rat cyclin B1. |
| Storage: | Store at 4C. Do not freeze. DO NOT FREEZE. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2 |
| Application Summary: | immunohistochemistry, Western Blot |
| Species Summary: | Hu, Mu, Rt |
| Alternate Names: | anti-CCNB1 antibody |
| Package Size: | 0.2 ml |
| Preservative: | Sodium Azide |
| General References: | 1. Morgan, D. O., et al.1995. Nature 374: 131 2. Norbury, C., et al. 1992. Annu. Rev. Biochem. 61: 441 3. Maity, A., et al. 1995. EMBO J. 14: 603 |
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