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| Catalog Code: | NB100-78501 |
| Product Name: | PTBP1 Antibody |
| Product Description: | Mouse Monoclonal anti-PTBP1 (3H7) |
| Clone: | 3H7 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Immunogen: | Recombinant human PTBP1 (full length) |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microgram per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | The 3H7 monoclonal antibody recognizes human PTBP1 also known as Polypyrimidine tract binding protein 1, Heterogeneous nuclear ribonucleoprotein I, and 57 kDa RNA-binding protein. PTBP1 is a ubiquitously expressed nuclear protein with a predicted molecular weight approximately 59.6 kD. The polypyrimidine tract binding protein (PTB) is an important regulator of alternative splicing that also affects mRNA localization, stabilization, polyadenylation, and translation. PTBP1 has been shown to interact with FUS, Caspase3, PKCa, Raver1, and HnRNP-L protein. The PTB gene contains 15 exons and spans 13.5 kb. The 3H7 antibody has been shown to be useful for Western blotting. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-Polypyrimidine tract binding protein 1 antibody, anti-Heterogeneous nuclear ribonucleoprotein I antibody, anti-hnRNP I antibody, anti-57 kDa RNA-binding protein PPTB-1 antibody, anti-PTB antibody |
| Package Size: | 0.1 mg |
| General References: | 1. Gil,A., et al. 1991. Genes Dev. 5 (7): 1224.2. Ghetti, A., et al. 1992. Acids Res. 20:3671.3. Romanelli, M. G., et al. 2000. Gene 255:267. |
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