| CatalogCode: | NB100-78485 |
| ProductName: | PRC1 Antibody |
| Product Description: | Mouse Monoclonal anti-PRC1 (6G2) |
| Clone: | 6G2 |
| Clonality: | Monoclonal |
| Immunogen: | Amino Acid: 1-150 |
| CrossReactivity: | Human. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 mug per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Cell cycle-dependent; nuclear, mitotic spindle, cell mid-body |
| Background: | PRC1 (also known as protein regulator of cytokinesis 1 and mitotic spindle-associated CDK substrate) is a member of the MAP65/ASE1 family with a molecular weight of approximately 72 kD. PRC1 localization changes with cell-cycle position and can be found in the nucleus, the mitotic spindle, and the cell mid-body. PRC1 is a mitotic spindle-associated CDK substrate protein required for cytokinesis and maintenance of the spindle midzone. PRC1 can be modified by phosphorylation and has been shown to interact with Cdc2 and Cdk2. The 6G2 antibody recognizes the human PRC1 protein and has been shown to be useful for Western blotting. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2b, kappa |
| Host_Name: | Mouse |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0 |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Protein regulator of cytokinesis 1 antibody, anti-Mitotic spindle-associated CDK substrate antibody, anti-Protein regulating cytokinesis 1 antibody, anti-PRC-1 antibody |
| ProteinTarget: | PRC1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | 1. Jiang, W., et al., 1998. Mol. Cell 2:877. 2. Mollinari, C., et al., 2002. J. Cell Biol. 157:1175. |
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