| CatalogCode: | NB100-78450 |
| ProductName: | Syk Antibody |
| Product Description: | Mouse Monoclonal anti-Syk (SYK-01) |
| Clone: | SYK-01 |
| Clonality: | Monoclonal |
| Immunogen: | Partial recombinant (amino acids 5-360) human Syk |
| CrossReactivity: | Mouse, Human, Rat. |
| Packaging: | 0.1 mg Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2 microgram/ml. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Cytoplasmic protein, widely expressed in hematopoietic cells |
| Background: | Syk is a cytoplasmic nbsp72 kD non-receptor tyrosine kinase that nbspis widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites. The SYK-01 monoclonal antibody (raised against amino acids 5-360 of human Syk) recognizes human, mouse, and rat and Syk and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG1, kappa |
| Host_Name: | Mouse |
| Buffer: | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| ListPrice: | 325 |
| AppSummary: | IHC, IP, WB |
| SpeciesSummary: | Mu, Hu, Rt |
| ALTnames: | anti-Spleen tyrosine kinase antibody, anti-protein tyrosine kinase SYK antibody |
| ProteinTarget: | Syk |
| PackageSize: | 0.1 mg |
| GeneralRef: | 1. Taniguchi, T., et al., 1991. J. Biol. Chem. 266:15790.2. Toyabe, S-L., et al., 2001.Immunology 103:164. |
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