| CatalogCode: | NB100-78434 |
| ProductName: | PKC Antibody |
| Product Description: | Mouse Monoclonal anti-PKC (PKC0103) |
| Clone: | PKC0103 |
| Clonality: | Monoclonal |
| Immunogen: | Protein kinase C from bovine brain |
| CrossReactivity: | Mouse, Rat, Human (Recognizes the alpha, beta, and gamma isoforms). |
| Packaging: | 0.5 ml Immunogen affinity purified Mouse antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 25 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | High expression in brain, isoforms vary in tissue expression |
| Background: | PKC, also known as protein kinase C, belongs to a kinase family involved in intracellular signaling processes. PKC isoforms are divided into three groups known as conventional (including PKC alpha, PKC beta1, PKC beta2 and PKC gamma), novel (including PKC epsilon, mu, theta, delta, eta), and atypical PKC isoforms (such as xi). Conventional PKC isoforms require calcium and diacylglycerol for activation, novel isoforms require diacylglycerol, and atypical isoforms require neither calcium nor diacylglycerol. Once activated by phosphorylation, the PKCs phosphorylate a large variety of substrates involved in cell differentiation, proliferation, and activation. The PKC0103 antibody recognizes human, mouse, and rat PKC and is useful for Western blotting and immunoprecipitation. |
| Storage: | Store at 4C. Do not freeze. DO NOT FREEZE. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG2a, kappa |
| Host_Name: | Mouse |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | 325 |
| AppSummary: | IP, WB |
| SpeciesSummary: | Mu, Rt, Hu |
| ALTnames: | anti-Protein kinase C antibody |
| ProteinTarget: | PKC |
| PackageSize: | 0.5 ml |
| GeneralRef: | 1. Liu, W.S., et al. 1998. Cell Signal 10:529.2. Way, K. J., et al. 2000. Trends Pharmacol. Sci. 21:181. |
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