| Catalog Code: | NB100-78401 |
| Product Type: | Primary Antibody |
| Product Name: | TIF1 beta Antibody |
| List Price: | 285 |
| Clonality: | Monoclonal |
| Gene ID: | 10155 |
| Host: | Mouse |
| Clone: | 20A1 |
| Isotype: | IgG1, kappa |
| Product Description: | Mouse Monoclonal anti-TIF1 beta (20A1) |
| Cross Reactivity: | Human. |
| Species Summary: | Hu(+) |
| Background: | TIF beta (transcription intermediary factor 1-beta) is an 88 kD member of the tripartite motif family. This protein contains three zinc binding domains, a RING domain, a B-box type 1 and type 2 domain, and a coiled-coil region. TIF beta is found in the nucleus and associates with specific chromatin regions. This protein forms a complex with KRAB-domain transcription factors and recruits setdbl to histone 3 to increase KRAB-mediated transcriptional repression. TIF beta has been reported to interact with setdbl and cbx3 proteins. The 20A1 monoclonal antibody has been shown to recognize the human TIF1 beta protein and has been shown to be useful for Western blotting. |
| Alternate Names: | anti-HB15 antibody |
| Purity: | protein G purified |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0 |
| Packaging: | 0.1 mg protein G purified Mouse antisera |
| PackageSize: | 0.1 mg |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 mug per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Application Summary: | Western Blot |
| Storage: | Store at 4C. Do not freeze. |
| General References: | 1. Ryan, R. F., et al., 1999. Mol. Cell. Biol. 19:4366. 2. Schultz, D. C., et al., 2002. Genes Dev. 16:919. 3. Moosmann, P. R., et al., 1996. Nucleic Acids Res. 24:4859. 4. Friedman, J. R., et al., 1996. Genes Dev. 10:2067. |
| WebLink: | www.novusbio.com/data_sheet/index/NB100 ... |
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