| CatalogCode: | | NB100-78385 |
| ProductName: | | RAR alpha Antibody |
| Product Description: | | Rabbit Polyclonal anti-RAR alpha |
| Clonality: | | Polyclonal |
| Immunogen: | | Recombinant (partial), N-terminal amino acids 1-100 |
| CrossReactivity: | | Human. |
| Packaging: | | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | Nuclear |
| Background: | | RAR alpha (retinoic acid receptor alpha) is a 51 kD member of the nuclear hormone receptor family, NR1 subfamily. This nuclear protein contains modulating, DNA-binding, and steroid binding domains, and has been reported to have multiple isoforms. RAR alpha is a nuclear receptor for retinoic acid that controls cell function by regulating gene expression and inducing profound effects on vertebrate development, acting as a morphogen and powerful teratogen. RAR alpha is increased by protein kinase C stimulation, and estrogen; decreased at G0/G1 to S phase of cell cycle and in lymphocytes by cellular activation. RAR alpha can be modified by phosphorylation and has been shown to interact with NCOA3 and NCOA6 co-activators leading to strong increases in the transcription of target genes. The Poly6168 antibody recognizes the N-terminal region of human RAR alpha and has been shown to be useful for Western blotting. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | | 285 |
| AppSummary: | | WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-Retinoic acid receptor alpha antibody, anti-RAR alpha antibody, anti-RAR alpha antibody |
| ProteinTarget: | | RAR alpha |
| PackageSize: | | 0.2 ml |
| GeneralRef: | | 1. Giguere, V., et al., 1987. Nature 330:624. 2. Petkovich, M., et al., 1987. Nature 330:444. |
| more information: | | company product webpage |