| CatalogCode: | | NB100-78374 |
| ProductName: | | SOCS2 Antibody |
| Product Description: | | Rabbit Polyclonal anti-SOCS2 |
| Clonality: | | Polyclonal |
| Immunogen: | | Recombinant (partial) , N-terminal |
| CrossReactivity: | | Human. |
| Packaging: | | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | Cytoplasm |
| Background: | | The SOCS2 (suppressor of cytokine signaling-2) protein is a 23 kD cytoplasmic protein that contains a SOCS box and an SH2 domain. SOCS2 has been shown to be involved in postnatal growth hormone signaling, IGF-1 signaling via the JAK/STAT pathway, and neuronal differentiation. SOCS2 is induced by erythropoietin, GM-CSF, IL-10, and IFN- gamma. SOCS2 has been shown to interact with the IGF-1 and growth hormone receptors. The Poly6153 antibody recognizes the N-terminal region of human SOCS2 and has been shown to be useful for Western blotting. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | | 285 |
| AppSummary: | | WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-Suppressor of cytokine signaling-2 antibody, anti-SOCS-2 antibody |
| ProteinTarget: | | SOCS2 |
| PackageSize: | | 0.2 ml |
| GeneralRef: | | 1. Minamoto, S., et al., 1997. Biochem. Biophys. Res. Commun. 237:79. 2. Dey, B., et al., 1998. J. Biol. Chem. 273:24095. 3. Metcalf, D., et al., 2000. Nature 405:1069. 4. Leung, K., et al., 2003. PNAS 100:1016. |
| more information: | | company product webpage |
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