| CatalogCode: | NB100-78349 |
| ProductName: | DNA-PKcs Antibody |
| Product Description: | Rabbit Polyclonal anti-DNA-PKcs |
| Clonality: | Polyclonal |
| Immunogen: | Recombinant (partial) |
| CrossReactivity: | Human. |
| Packaging: | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Nuclear |
| Background: | DNA-protein kinase catalytic subunit (DNA-PKcs) also known as DNA-activated kinase is a nuclear 460-470 kD serine threonine kinase involved in double-stranded DNA break repair, VDJ recombination, and transcriptional modulation. DNA-PKcs must bind DNA ends to become active. DNA-PKcs is modified by phosphorylation and has been shown to interact with Ku70/Ku80, KIP, DNA-ligase IV, and XRCC4 proteins. The Poly6126 antibody recognizes human DNA-PKcs and has been shown to be useful for Western blotting. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-DNA-protein kinase catalytic subunit antibody, anti-DNA-activated protein kinase antibody, anti-DNA-dependent protein kinase antibody |
| ProteinTarget: | DNA-PKcs |
| PackageSize: | 0.2 ml |
| GeneralRef: | 1. Hartley, K., et al., 1995. Cell. 82:849. 2. Connelly, M., et al., 1996. Gene. 175:271. 3. Douglas, P., et al., 2002. Biochem. J. 368:243 4. Calsou, P., et al., 2003. J. Mol. Biol. 326:93. |
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