| CatalogCode: | | NB100-78341 |
| ProductName: | | BAP37 Antibody |
| Product Description: | | Rabbit Polyclonal anti-BAP37 |
| Clonality: | | Polyclonal |
| Immunogen: | | Recombinant (partial) , C-terminal |
| CrossReactivity: | | Mouse, Human. |
| Packaging: | | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a starting dilution of 1:100. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | Inner mitochondrial membrane, integral membrane protein |
| Background: | | BAP37, (also known as B-cell receptor-associated protein, repressor of estrogen receptor activity, and prohibitin 2) is a 37 kD erythrocyte band 7 integral membrane protein that contains an SPFH domain. BAP37 is located in the inner mitochondrial membrane that selectively potentiates the inhibitory effectiveness of antiestrogen-occupied ER. BAP37 plays a possible role in cell aging and acts as a mitochondrial protein chaperone. This protein has been shown to interact with the estrogen receptor, prohibitin, and IgM. The Poly6118 antibody has been shown to be useful for Western blotting of the human and mouse BAP37 protein. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | | 285 |
| AppSummary: | | IF, WB |
| SpeciesSummary: | | Mu, Hu |
| ALTnames: | | anti-B-cell receptor-associated protein antibody, anti-Repressor of estrogen receptor activity (REA) antibody, anti-Prohibitin 2 (Phb2) antibody |
| ProteinTarget: | | BAP37 |
| PackageSize: | | 0.2 ml |
| GeneralRef: | | 1. Terashima, M., et al., 1994. EMBO J. 13:3782. 2. Montano, M., et al., 1999. PNAS 96:6947 3. Nijtmans, L., et al., 2000. EMBO J. 19:2444. 4. Piper, P., et al., 2002. Aging Cell 1:149. |
| more information: | | company product webpage |
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