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| Catalog Code: | NB100-78281 |
| Product Name: | p90 Rsk Antibody |
| Product Description: | Rabbit Polyclonal anti-p90 Rsk |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Recombinant (partial), N-terminal |
| Cross Reactivity: | Human. |
| Packaging: | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Background: | p90 Rsk (ribosomal protein S6 kinase) is a 90 serine/threonine kinase and a member of the S6 kinase subfamily. This kinase is normally cytosolic but is transiently targeted to the membrane after activation. p90 Rsk phosphorylates a range of substrates including ribosomal protein S6 and is activated by the extracellular signal kinases ERK 1/2, PDK-1,and MAPK kinase cascade. p90 Rsk is phosphorylated and can interact with 14-3-3 beta, and ERK 1/2 under quiescent conditions p90 Rsk is decreased upon mitogen stimulation. The Poly6048 antibody recognizes the N-terminal region of human p90 Rsk and has been shown to be useful for Western blotting. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-90 kD ribosomal protein S6 kinase antibody, anti-ribosomal S6 kinase 1 antibody, anti-RSK-1 antibody |
| Package Size: | 0.2 ml |
| General References: | 1. Chrestensen, C., et al., 2002. J. Biol. Chem. 277:27733. 2. Moller, D., et al., 1994. Am. J. Physiol. 266, C351. 3. Franklin, R., et al., 1995. J. Immunol. 154:4965. 4. Cavet, M., et al., 2003. J. Biol. Chem. 278:18376. |
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