| CatalogCode: | | NB100-78275 |
| ProductName: | | GSK-3 beta Antibody |
| Product Description: | | Rabbit Polyclonal anti-GSK-3 beta |
| Clonality: | | Polyclonal |
| Immunogen: | | Recombinant (partial) , C-terminal |
| CrossReactivity: | | Mouse, Human, cross-reacts with GSK-3 alpha. |
| Packaging: | | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | | Testis, thymus, prostate, ovary. Weak expression in lung, brain, kidney |
| Background: | | GSK-3 beta (glycogen synthase kinase-3 beta) is a 49 kD serine/threonine kinase that is a member of the CDC2/CDKX subfamily. This protein is expressed in the testis, thymus, prostate, and ovary, with weak expression in lung, brain, and kidney. GSK-3 beta is thought to participate in the insulin and Wnt signaling pathway and has been shown to phosphorylate c-jun to reduce DNA binding. GSK-3 beta can be modified by AKT phosphorylation which inhibits function. This protein has been shown to interact with axin and GBP/FRAT. The Poly6042 antibody recognizes human and mouse GSK-3 beta and is cross-reactive with GSK-3 alpha. The Poly6042 antibody has been shown to be useful for Western blotting. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | | 285 |
| AppSummary: | | WB |
| SpeciesSummary: | | Mu, Hu |
| ALTnames: | | anti-Glycogen synthase kinase-3 beta antibody, anti-GSK3beta antibody, anti-GSK 3beta antibody |
| ProteinTarget: | | GSK-3 beta |
| PackageSize: | | 0.2 ml |
| GeneralRef: | | 1. Stambolic, V., et al., 1994. Biochem. J. 303:701. 2. Delcommenne, M, et al., 1998. PNAS 95:11211. |
| more information: | | company product webpage |
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