| CatalogCode: | NB100-78260 |
| ProductName: | MCM4 Antibody |
| Product Description: | Rabbit Polyclonal anti-MCM4 |
| Clonality: | Polyclonal |
| Immunogen: | Peptide-KLH (SRRGRATPAQTPRSED) |
| CrossReactivity: | Human. |
| Packaging: | 0.2 ml Immunogen affinity purified Rabbit antisera |
| Uses: | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 mul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application. |
| Control: | Nuclear |
| Background: | The MCM4 protein (minichromosome maintenance protein 4) is a nuclear 100 kD DNA-dependent ATPase. The MCM4 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM4 together with MCM6 and MCM7 have DNA helicase activity. MCM4 can be modified by phosphorylation by CDK2. Phosphorylation of MCM4 inhibits DNA replication. MCM4 has been reported to interact with the MCM6 and MCM7 (to form a 600 kD complex with helicase activity) and CDK2. The Poly6024 antibody recognizes human MCM4 and has been shown to be useful for Western blotting. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Minichromosome maintenance protein 4 antibody |
| ProteinTarget: | MCM4 |
| PackageSize: | 0.2 ml |
| GeneralRef: | 1. Hu, B., et al., 1993. Nucleic Acids Res. 21:5289. 2. Ishimi, Y. 1997. J. Biol. Chem. 272:24508. 3. Ishimi, Y., et al., 2003. J. Biol. Chem. 278:24644. |
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